The immune system provides constant surveillance for the body, aiming to spot and eliminate disease-causing microbes or cancerous cells. But tumor cells develop many features that help them hide from ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

Immunotherapy. 2012;4:1063-1074. DCs transduced with IL-4 vectors 105,106 DCs transduced with IL-10 vectors 107–109 DCs transduced with viral IL-10 vectors 110 DCs transduced with CTLA4–Ig vectors 104 ...

Scientists have uncovered how a vitamin A metabolite can suppress anti-cancer immunity. Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have uncovered new ...

Clinical effectiveness of immune therapies of solid tumors requires a) the induction or expansion of T cells able of recognizing multiple variants of cancer cells present in each cancer patient, and b ...

Scientists have uncovered a troubling role for a vitamin A byproduct in cancer, which appears to help tumours slip past the ...

Retinoic acid suppresses immune defenses against cancer, but a new drug KyA33 boosts vaccine success and slows tumor growth ...